Acne Treatment
Medical Policy: 02.01.29
Original Effective Date: April 2006
Reviewed: December 2008
Revised: June 2007
This policy applies to all products unless specific contract
limitations, exclusions or exceptions apply. Please refer to the member's coverage
manual for benefit availability. Managed care guidelines related to referral authorization,
and precertification of inpatient hospitalization, home health, home infusion and
hospice services apply.
Description:
Acne is a very common disorder of the pilosebaceous follicles that primarily affects adolescents and young adults and may be classified as inflammatory or noninflammatory. Acne is characterized by comedones, nodules and eruptions of papules, pustules, and nodulocystic lesions. Lesions are found in areas where there is the greatest concentration of sebaceous glands, such as the face, neck, and upper part of the trunk. Conventional treatment of active acne usually consists of a good skin care regimen, topical benzoyl peroxide, topical antibiotics or topical retinoids, oral antibiotics, and less often, oral retinoids.
Pulse-dye lasers have been investigated for the treatment of active inflammatory acne. Laser therapy at various irradiation levels. (e.g., low and mid-level irradiation lasers and long pulse diode lasers) has been used to destroy active acne lesions enlarged sebaceous glands.
Other treatments being investigated for the treatment of active acne involve the use of light in specific wavelengths. Interest in using light as a treatment may be related to the positive short term effects some acne sufferers have experienced from exposure to sunlight. Investigators have worked with intense blue or violet light in the 405-425 nanometer wavelength range and in the red visible spectrum of 660 nanometer range.
Photodynamic therapy, also known as photochemotherapy, using 5-aminolevulinic acid followed by exposure to ultraviolet light has also been investigated for the treatment of acne. While Photodynamic therapy has been used successfully for the treatment of actinic keratoses and other lesions it has not been proven safe and effective for the treatment of acne.
Treatment of active acne is distinct from the treatment of acne scarring which may occur from tissue damage after inflammatory lesions subside. The treatment of acne scarring is considered cosmetic in nature and therefore is not a contract benefit.
Policy:
Treatment of active acne with the following methods may be considered medically necessary;
- Topical treatments such as benzoyl peroxide, antibiotics, or retinoids
- Oral antibiotics for more severe cases or if a trial of topical treatments alone has failed
- Chemical peels, including epidermal exfoliation (epidermal peels) or cryotherapy with liquid nitrogen or dry ice when a trial of topical retinoid treatment, topical and oral antibiotic therapy have failed
- Combined oral estrogen and progestin for female patients who have failed conservative treatments listed above
- Oral retinoids for severe treatment resistant cases
Pulse-dye laser or any other type of laser system, intense visible spectrum light, or photodynamic therapy in conjunction with 5-aminolevulinic acid are all considered investigational for the treatment of active acne.
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Procedure Codes and Billing
Guidelines:
- To report provider services, use appropriate CPT* codes, Alpha Numeric (HCPCS level 2) codes, Revenue codes, and/or ICD-9-CM diagnostic codes.
- 17999 Unlisted procedure, skin, mucous membrane and subcutaneous tissue
- 96999 Unlisted special dermatological service or procedure
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Selected References:
- The Medical Policy Reference Manual (MPRM) developed by the Blue Cross Blue Shield Association Health Management Systems, based on Technology Evaluation Center (TEC) criteria.
- Institute for Clinical Systems Improvement, Inc. The Acne Guideline for Patients and Families. February 2005. Available on line at www.icsi.org/index.asp
- ECRI. Laser Therapy for Acne. Plymouth Meeting (PA): ECRI Health Technology Information Service; 2005, June 17. 11 p (ECRI Hotline Response). Also available: http://www.ecri.org.
- Seaton, E D, Charakida, A, et al. Pulsed-dye laser treatment for inflammatory acne vulgaris: randomised controlled trial. Lancet. 2003;362(9393):1347-52.
- Orringer JS, Kang S, et al. Treatment of acne vulgaris with a pulsed dye laser: a randomized controlled trial. JAMA. 2004; 291(23):2834-9.
- Harper J An update on the pathogenesis and management of acne J Am Acad Dermatol 2004 Jul;51(1 Suppl):S36-8.
- Gold MH, Rao J, Goldman MP, et al. A multicenter clinical evaluation of the treatment of mild to moderate inflammatory acne vulgaris of the face with visible blue light in comparison to topical 1% clindamycin antibiotic solution. J Drugs Dermatol. 2005;4(1):64-70.
- Strauss JS, Krowchuk DP, Leyden JJ, et al. American Academy of Dermatology. Guidelines of care for acne vulgaris management. J Am Acad Dermatol 2007; 56:651-63. Available at: http://www.aad.org/NR/rdonlyres/8D4D2DDB-7176-4202-808E-28D67334B3E4/0/AcneVulgaris.pdf. Accessed November 18, 2008.ECRI
- ECRI. Laser Therapy for Acne. Plymouth Meeting (PA): ECRI Health Technology Information Service; 2007 June 5. 13p. (ECRI Hotline Response). Also available: http://www.ecri.org.
- ECRI. Blue Light Therapy for Acne. Plymouth Meeting (PA): ECRI Health Technology Information Service; 2007 June 4. 9p. (ECRI Hotline Response). Also available: http://www.ecri.org.
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New information or technology that would be relevant for Wellmark to consider when this policy is next reviewed may be submitted to:
Wellmark Blue Cross and Blue Shield
Medical Policy Analyst
Station 304
636 Grand Ave
Des Moines, Iowa 50309
*Current Procedural Terminology © 2009 American Medical Association. All Rights Reserved.
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